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We had two fantastic visiting speakers today MERMan alumnus @rowancallumg.bsky.social spoke about his current work with viral cheating in influenza with @asherleeks.bsky.social And @lavishaparab.bsky.social talked about phage infection trade-offs Thanks to @microbesng.bsky.social for our snacks!
@rowancallumg.bsky.social and @liyamiksovsky.bsky.social demonstrating our newest lab tradition - creating virus snowflakes (designed by @socialinfluenza.bsky.social ) out of submitted grants and fellowships. 🧪 #socialviruses
Great thread! All good, but this does grab the attention: "our findings with ΔnudJ suggest future anti-evolution drug strategies could suppress spontaneous resistance evolution not only through minimizing resistance mutations but also by specifically limiting access to the fittest mutations."
Come join us at UBC for all things virus-virus interactions & evolution!
6mo
7mo
@rowancallumg.bsky.social @knightjar.bsky.social @rokkrasovec.bsky.social et al. study the antimutator ΔnudJ to highlight the value of considering mutation rate and mutational spectrum to understand the evolution of mutation rate-modifying alleles. 🔗 doi.org/10.1093/molbev/msaf182 #evobio #molbio
9mo
1mo
9mo
Come work/study in a wonderful department with a great group leader!!!
1mo
Abstract. The rate of spontaneous mutation is a key factor in determining the capacity of a population to adapt to a novel environment, for example, a bact
doi.org
Antimutator and Mutational Spectrum Effects Can Combine to Reduce Evolutionary Potential in Escherichia coli ΔnudJ
MERMan Research Group (University of Manchester)
Asher Leeks
Molecular Biology and Evolution
Zamin Iqbal
Rowan Green
Rowan Green
New paper out @molbioevol.bsky.social on antimutator Ecoli, mutational spectra and the distribution of fitness effects of antibiotic resistance with @knightjar.bsky.social @rokkrasovec.bsky.social and others @mermanchester.bsky.social doi.org/pzfm Read🧵for highlights and fun stats (1/13)
The Social Lives of Viruses is coming to Vancouver, Canada, from 4th-8th August 2026! This is a free meeting dedicated to all aspects of virus-virus interactions & evolution. To apply: socialviruses.zoology.ubc.ca @sociovirology.bsky.social #socialviruses #evosky #lovevirology #virosky
We're recruiting! We're looking for two graduate students to join us at UBC in Vancouver. Fully funded and open to global applicants, with flexible start-date. Topics include theory, bioinformatics, and microbiology. More details: asherleeks.com/apply #socialviruses #evosky #virosky 🧪
9mo
1mo
1mo
Abstract. The rate of spontaneous mutation is a key factor in determining the capacity of a population to adapt to a novel environment, for example, a bact
doi.org
Antimutator and Mutational Spectrum Effects Can Combine to Reduce Evolutionary Potential in Escherichia coli ΔnudJ
Rowan Green
Asher Leeks
Asher Leeks