1️⃣ www.nature.com/articles/s41...
Adhesion-driven rigidity transition decoupled from density-driven jamming triggers epithelial organization in embryonic tissues
💫 led by @crisp-c.bsky.social, Adrián Aguirre-Tamaral, and me
EMBL graduated its biggest class ever at the end of April, celebrating with 60 fellows who submitted or defended their theses over the past 12 months.
Representing 22 different countries, EMBL graduates continued to show a diversity in science as well as background. Congratulations graduates!
Tissue phase transitions are key to morphogenesis. Now adhesion-driven rigidification is identified as key to epithelial organization but only if uncoupled from density-driven jamming.
2️⃣ www.nature.com/articles/s41...
Tissue rigidity phase transition shapes morphogen gradients
💫 led by @cami-autorino.bsky.social
Tissue phase transitions in development: more than just mechanics
In this Review, @nicolettapetridou.bsky.social, @laura-rustarazo.bsky.social and @karengrace12.bsky.social discuss tissue phase transitions during development: doi.org/10.1242/dev....
💫 Our paper is now published at @natcellbio.nature.com! So excited about this work done during my PhD at @embl.org in the group of @nicolettapetridou.bsky.social along with our great collaborators! 🐟🎉
Glad to see this out in its final form!
www.nature.com/articles/s41...
What changed since the preprint? Wonderful experiments disentangling the effect of receptor binding vs tissue porosity on Nodal diffusion, plus one of the smoothest review experiences! Thanks @natcellbio.nature.com & reviewers 🙏
...and here is @embl.org's press release on the two latest papers by @nicolettapetridou.bsky.social's group on how rigidity phase transitions guide 1️⃣ tissue organisation and 2️⃣ morphogen gradients in embryonic tissues. 🐟
This work represents the core of my PhD work with @nicolettapetridou.bsky.social at @embl.org and would not have been possible without my amazing colleagues + collaborators (especially my co-authors @crisp-c.bsky.social and Adrián!). Thank you also to the reviewers and everyone else who contributed.
