Official Account for Christina Woo’s Lab at Harvard CCB| chembio, protein mods, chemoproteomics, TPD | Student-run account | posts by Christina signed CMW
The Woo Lab
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The Woo Lab was proud to hood the three PhD’s of the class of 2026! Cheers 🥂 and congratulations 🎉 to Dr. Vanessa Dippon, Dr. Alison Mody, and Dr. Hannah Lloyd! 🫶🏼
We hope you all enjoyed Christina's talk as much as we enjoy sharing our science! Seems like it was a packed house 🫡
🙌🏼🩵
👋🏼👋🏼👋🏼
Another Woo Lab Dr. is in: Congrats to our newest Ph.D, Dr. Alison Mody!🫡 Cheers to a wonderful Ph.D. and a sweet (pun intended) thesis talk, all the world’s alpacas are celebrating with you in spirit 🦙🩵🟦💐🎉
we hope you enjoyed this paper as much as we do! 😉😘
if you’re interested in working with an allosteric ligand, reach out to Prof. Woo 🫡 we’re more than happy to share 🙌🏼🩵✨ #thefutureisallostery #CRBN #TPD
Roses are red, GlcNAc is blue, sugar is sweet, and we want YOU to read our latest in @natcomms.nature.com — where we identify small-molecules that disrupt OGlcNAc homeostasis via RNA splicing. Congrats Steven (@scheng23.bsky.social) and all the authors! 🟦🍭❤️ www.nature.com/articles/s41...
Exciting new work from @thewoolab.bsky.social just out @nature.com
www.nature.com/articles/s41...
Authors report drug repurposing screens against O-GlcNAc cycling enzymes, finding kinase inhibitors that act as splicing modulators to disrupt O-GlcNAc homeostasis and downregulate OGT and OGA. These ...
An allosteric site on the E3 ligase adapter cereblon can be targeted to modulate the efficacy of cereblon in targeted protein degradation applications.
Pour a glass of champagne AND red Bordeaux—Our newest work with GSK @scripps.edu is out in @nature.com! Here we describe SB-405483, the first allosteric CRBN ligand which potentiates neosubstrate degradation. Congrats Vanessa and all authors! 🍷💫💐 www.nature.com/articles/s41...
Nature research paper: Identification of an allosteric site on the E3 ligase adapter cereblon
go.nature.com/3NHFcPj
Happy to meet Christina Woo @thewoolab.bsky.social at the meeting of the JPS meeting in Osaka. Looking forward to hearing your talk.
We are very happy that Christina Woo (@thewoolab.bsky.social) visited us for a very well-attended LED3 Lecture. She talked about the importance of C-terminal cyclic imides as natural #degrons for protein degradation with important implications for targeted protein degradation.
#TPD #ChemBio #ChemSky
An allosteric site on the E3 ligase adapter cereblon can be targeted to modulate the efficacy of cereblon in targeted protein degradation applications.
