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Exciting new work from @thewoolab.bsky.social just out @nature.com www.nature.com/articles/s41...
5mo
An allosteric site on the E3 ligase adapter cereblon can be targeted to modulate the efficacy of cereblon in targeted protein degradation applications.
www.nature.com
Identification of an allosteric site on the E3 ligase adapter cereblon - Nature
Carolyn Bertozzi
