Now out @natbiotech.nature.com ! Do lncRNAs commonly bind 1000s of genomic sites? Maybe they do, but the dozens of studies that report genomic binding maps of lncRNAs are deeply flawed, with probes binding suprious DNA sites rather than RNA-bound ones.
💥 Great fun writing this #review with @alejotorrescano.bsky.social
– reflecting on the emergence of #pancreatic #lineages in the #embryo through the lens of #plasticity -
Just out online ➡️ rdcu.be/fiw3c
@wellcometrust.bsky.social @kingscollegelondon.bsky.social @kingslsm.bsky.social
Excited to share our new study on CpG islands (CGIs) regulation by transcription factors (TFs)! CGIs drive most transcription initiation with unclear regulation. We find that chromatin-opening TFs are key players—following a surprisingly simple rule. 🧵 www.biorxiv.org/content/10.6...
1/9
Excited to share our Nature Genetics Research Briefing on how the repetitive genome helps shape leukemia stemness.
We found that transposable elements sustain stem-like states in AML and predict patient outcomes.
www.nature.com/articles/s41...
Thrilled to present our comparative study on the evolution of zygotic genome activation (ZGA)!! 🥚🧬
Amazing PhD work of @campobes.bsky.social together with @fedemantica.bsky.social and many collaborators! @melisupf.bsky.social @crg.eu. Thread below 1/15
www.biorxiv.org/content/10.6...
Associate Senior Lecturer/Assistant Professor position in Molecular Microbiology available at Lund University, Sweden:
lu.varbi.com/en/what:job/...
A week left to apply to our fully funded PhD studentship (thanks to the Generation Trust!) - entry point updated to either June or October (so no worries if you are currently finishing your MPhil!). Don't hesitate to contact me with any questions about the opportunity or the project itself.