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Excited to share our Nature Genetics Research Briefing on how the repetitive genome helps shape leukemia stemness. We found that transposable elements sustain stem-like states in AML and predict patient outcomes. www.nature.com/articles/s41...
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By mapping chromatin accessibility over transposable elements (TEs) across normal hematopoietic cells and the various cell types of primary acute myeloid leukemia (AML), we identified TE subfamilies w...
www.nature.com
Alterations of chromatin state at transposable elements rewire stemness in acute myeloid leukemia - Nature Genetics
Mathieu Lupien