Original: Drs. De Vera, Moayedi et al. ( @utoronto.ca) found that pain intensity, pain unpleasantness, and secondary hyperalgesia show moderate-to-good reliability in a PHP paradigm, but only secondary hyperalgesia area remains stable across sessions
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Original: Drs. Guo, Aplin evaluated a soft, metal-free nerve cuff for ionic direct current delivery in healthy and pathological pain models
— iDC might represent a potential treatment for chronic pain
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Original: Drs. Bembich, Maestro, et al. explored sex-related differences in neonatal nociception, an area that remains relatively understudied despite well-documented disparities in adult pain experience.
FULL: www.jpain.org/article/S152...
Original: Drs. Horvat and team at University of Maribor, using electrical pain stimulation, explored neurophysiological mechanisms mediating the influence of romantic partner’s presence on acute pain perceptions.
FREE: www.jpain.org/article/S152...
Original: Dr. Wilson, Meints, et al. examined how chronic pain and gender-related stigma intersect in cisgender women with chronic pelvic pain and their associations with pain and psychosocial factors.
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Original: Drs. Morris,Goodin et al. ( @vanderbilt.edu) showed differential prognostic importance of biopsychosocial factors for high-impact chronic pain incidence, persistence, and recovery using a machine learning approach
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Original: Drs. julieji.bsky.social, Hughes, et al. investigated the impact of mental imagery simulations of threat on endogenous pain modulation in n = 71 healthy participants using a cuff-pressure algometry protocol.
FREE: www.jpain.org/article/S152...
Featured: Drs. Du, Tang et al. found that SCFA-FFAR2 signaling reduces visceral hypersensitivity in both sexes, but only males rely on FFAR2-dependent suppression of IL-17RA signaling in the anterior cingulate cortex
FREE: www.jpain.org/article/S152...
Original: Dr. Thomas, @luanacolloca.bsky.social, et al. tested the hypotheses that pain resilience is negatively associated with pain interference, and pain resilience is positively associated with placebo effects via reinforced expectations of analgesia.
FULL: www.jpain.org/article/S152...
Original: Drs. Yamin, Edwards, et al. examined the extent to which pain catastrophizing contributes to the association between posttraumatic stress symptoms and pain outcomes in patients with chronic low back pain.
FULL: www.jpain.org/article/S152...
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This study explored sex-related differences in neonatal nociception, an area that remains relatively understudied despite well-documented disparities in adult pain experience. The research aimed to…
The supportive presence of a significant other can act as an efficient analgesic. However, neurophysiological mechanisms of this effect have not been adequately explored. The current EEG study, using…
Women with chronic pelvic pain (CPP) often experience stigma related to both their gender identity and chronic pain status, as symptoms are frequently dismissed, disbelieved, or attributed to…
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High-impact chronic pain (HICP) affects over 17 million U.S. adults and follows highly variable courses. To date, the relative importance of biopsychosocial predictors of HICP incidence, persistence,…
Mental imagery-based simulations of threat can evoke “as-if-real” emotional and motivational responses, which may alter top-down pain processing. This study investigated the impact of mental imagery…
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Expectations about medical treatment are important prognostic indicators of treatment success and play a key role in shaping individual pain experiences. Placebo interventions can modify these…
Posttraumatic stress symptoms (PTSS) are prevalent among individuals with chronic low back pain (CLBP) and are associated with worse pain-related outcomes. Pain catastrophizing is a cognitive factor…
Sex differences in visceral hypersensitivity (VH) has been demonstrated, while the underlying mechanism needs to be elucidated. A sodium dextran sulfate (DSS)-induced acute colitis mouse model was…
Longitudinal and interventional pain studies require reliable outcome measures. Self-reported pain intensity and unpleasantness are gold standard pain assessment measures. Additionally, the extent of…
