Royal Society University Research Fellow | NUAcT Fellow @ Newcastle University @mhd-newcastle.bsky.social
Investigating mycobacterial transport systems
#structuralbiology #microbiology
Instagram @kshbeckham
Kate Beckham
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Starting the afternoon session with a fun, interactive talk from @kateduncan.bsky.social exploring the chemical language of microbes🦠
Great talk from @kasiamic.bsky.social kicking off the Microbiology Research Celebration. @mhd-newcastle.bsky.social @cbcb-newcastle.bsky.social @medicalsciencesncl.bsky.social
Some very cool simulations, look at those little guys climb that ladder!
#MolecularNodes
Just over a week left to apply for this #PhD #studentship on S-layers and #AMR!
Please share and if you want to know more, get in touch!
Thanks to the organisers of the ‘2026 Celebration of Microbiology’ for letting me talk about RodA in Bacillus subtilis!
It was great to share a summary of the last 3 years with @seamusholden.bsky.social and @henrikstrahl.bsky.social
Our latest paper ‘Ecological context for bacterial natural products’ is now out in the Royal Society of Chemistry @natprodreports.rsc.org
International effort with @jonathanparra.bsky.social, Marla I Macias-Contreras & Dulce Guillen Matus #puravida #naturalproducts
pubs.rsc.org/en/Content/A...
@agnese75.bsky.social's work is out. She shows that under iron starvation M. tuberculosis splits flux through the Krebs cycle and secretes metabolites, akin of fermentation. Why is this important? Metabolic flexibility is what makes it so hard to kill in vivo.
elifesciences.org/reviewed-pre...
Now online. Great collaboration with the Tidow lab @seegerlab and the @embl SAXS beamline.
Capturing transient states of heterodimeric ABC transporter TM287/288 by time-resolved small-angle X-ray scattering: Biophysical Journal www.cell.com/biophysj/ful...
Kate Beckham
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First paper for PhD student in the Bolam / Lowe labs Natalia Łoś on a the characterisation of a new CBM family that binds (beta) mannan! #glycotime @natalia-los.bsky.social 🥳🥳
link.springer.com/article/10.1...
Kate Beckham
E subunit-enabled ENZYME YOGA. Structures of catalytically active, asymmetric, hybrid acyl-CoA carboxylase, essential in M. tuberculosis @edumullapudi.bsky.social & @matthiaswilmanns.bsky.social & Minh Thai.
www.nature.com/articles/s42...
see also Liang et al.
www.pnas.org/doi/10.1073/...
Covering: This review covers literature from 2015 to present.It is widely recognised that there is a significant gap between bacterial natural product potential and detected/described products. As suc...
