E subunit-enabled ENZYME YOGA. Structures of catalytically active, asymmetric, hybrid acyl-CoA carboxylase, essential in M. tuberculosis @edumullapudi.bsky.social & @matthiaswilmanns.bsky.social & Minh Thai.
www.nature.com/articles/s42...
see also Liang et al.
www.pnas.org/doi/10.1073/...
Structural analysis of endogenously expressed proteins in Mycobacterium smegmatis reveals an asymmetric short-chain/long-chain hybrid acyl‑CoA carboxylase that comprises 16 subunits with (AccA3)4–AccE...