What would happen if Darwin, Russell Wallace and Koch walked into a bar?
We present our new way to study mycobacteria, employing a macroevolution framework (species not strains). Possibilities are endless!! Thanks to Fernanda Subtil for pushing this.
elifesciences.org/articles/101...
Phage satellites induced by virulent phages are mobilized by natural competence leading to phage resistance in a new host | Nature Communications https://www.nature.com/articles/s41467-026-72928-1
Very excited this work by Victor and Jakson @crick.ac.uk is out!! started many years ago with @jvaubourgeix.bsky.social They generated Mtb-Timer, a fluorescent reporter in Mtb as a proxy for Mtb replication and measure antibiotic responses Mtbhttps://journals.asm.org/doi/10.1128/msystems.01796-25
The heterogeneous selection landscape of genome evolution in prokaryotes www.pnas.org/doi/10.1073/... #jcampubs
You are an ambitious young scientist, on the verge to independence, in a research field related to our Cluster of Excellence @cmfi.bsky.social “Controlling Microbes to Fight Infections”? Join our vibrant, interactive scientific community in Tubingen. Repost and apply!
www.nature.com/naturecareer...
Join us in beautiful Madison WI! In addition to the postdoc call I previously announced, I am seeking applicants for a Scientist position. IMO this position is best suited for someone who successfully completed their postdoctoral training, see here for more details: jobs.wisc.edu/jobs/scienti...
Excited to host @uwmadison.bsky.social Drew Hryckowian @a-hryckowian.bsky.social today. Looking forward to hearing all about microbiome-pathogen-host with focus on Clostridioides difficile. And of course, the unavoidable and multidirectional flow of nutrients and chemistry between these.
@agnese75.bsky.social's work is out. She shows that under iron starvation M. tuberculosis splits flux through the Krebs cycle and secretes metabolites, akin of fermentation. Why is this important? Metabolic flexibility is what makes it so hard to kill in vivo.
elifesciences.org/reviewed-pre...
Thrilled to see Sarah Dallo defending her PhD in the lab. @scripps.edu @wertheimufscripps.bsky.social Congratulations!! Hard work, dedication and attitude. She moved to my lab after 3 years in another lab. Tough transitions can be managed! Two papers on the way.
Bacterial immune proteins have repeatedly evolved to become parts of eukaryotic immunity. But how?
Our new preprint uncovers a recent horizontal transfer event & shows how eukaryotes co-opted a toxic bacterial immune protein 🦠🧪🧵 1/
The Cluster of Excellence EXC 2124 “Controlling Microbes to Fight Infections” (CMFI) at the University of Tübingen invites applications for Indepen...
Using macroevolution, species not strains, uncovered important diversity in how mycobacteria respond to and resist antibiotics, revealing novel resistance determinants.
