Could molecules from long-extinct species help fight #antibioticresistance? Researchers are exploring #MolecularDeextinction to uncover novel #antimicrobials, including #peptides from the #extinct moa. A PNAS Core Concept piece: https://ow.ly/hxAy50Z6fHF
#evolution #genome
📢 #KRAS degradation induces rapid lung #cancer regression in preclinical mouse models: A study by #IRBBarcelona & @ciccancer.bsky.social demonstrates that eliminating mutated KRAS protein using #PROTACs induces rapid tumour regression in mouse models of lung adenocarcinoma.
➡️ https://bit.ly/4dFWhm1
Forgot spike-ins in your lrRNA-seq experiment? 😅 No problem! Our TUSCO benchmarks your transcript models using endogenous single-isoform genes as internal ground truth. Integrated in SQANTI3 for human & mouse. 🧬 Just out in @natcomms.nature.com @pacbio.bsky.social @nanoporetech.com
rdcu.be/fkZCb
www.biorxiv.org/content/10.6...
With Eugene Koonin, we wrote a rather comprehensive review on the origin, evolution and organization of the #virosphere. We describe all 10 viral realms and the logic behind them, and so much more. Check it out! comptes-rendus.academie-sciences.fr/biologies/ar...
I am writing my first review as a last author without collaborating with any of my previous mentors. Scary... I feel like moving alone far from my parents for the first time 😅
Please, don't write cover letters with AI when applying to jobs. Selection committees see so many of them in a short time window and artificial constructions become too evident.
I prefer an honest cover letter with grammar errors, made with effort, rather than a fake one.
On this 1st April I'm happy to release a technical report from our startup MirageBio, describing a new protein structure model with state-of-the-art performance.
jgreener64.github.io/posts/techni...