For students in the Paris region: free mental health support is available, and sessions can be held in Italian, Spanish or English if requested. Don't hesitate to share this info! www.apaso.fr/les-consulta...
Capolavoro 🎨 alert 🚨! What is the role of gene body methylation in invertebrates? Despite extensive speculation linking it to plasticity and environmental responses, its mechanistic effects and heritability remain unclear. Our take out in @natecoevo.nature.com: www.nature.com/articles/s41... 1/
www.nature.com
Experiments in the cnidarian Nematostella vectensis show a role of gene body methylation in transposable element suppression and that epigenetic inheritance is constrained by chromatin context and tra...
Human embryo editing against disease is unsafe and unproven — despite rosy predictions www.nature.com/articles/d41...
www.nature.com
Pitfalls of heritable genome editing undermine theoretical benefits.
A strong hint from human genetics that changes in DNA methylation may be causal for normal aging. This is the direction that aging (and cancer) research needs to go!
www.nature.com/articles/s41...
This study investigates the consequences of hypermethylation in a progeria syndrome caused by gain-of-function DNMT3A mutations, finding effects on adult stem cell function.
Rising CO2 levels? Simply grow more ants, of course
www.biorxiv.org/content/10.6...
I finish books, even ones I don’t enjoy, but there was one I just couldn’t get through: gatsby. Today, a second book makes the list: Wuthering heights. Why are these so popular ? I guess I’ll never know
www.biorxiv.org
Julien Richard Albert
Kevin Mitchell
Choice words from Dr. Szostak here.
And while I am no Nobel Prize-winning scientist, I identify with the same quandary as an immigrant, moving here in 2009 and (proudly) becoming a citizen in 2023.
I, too, don't recognize that country anymore 😢🇺🇸🧳🛫.
newsletter.ofthebrave.org/p/im-a-nobel...
Julien Richard Albert
Our latest work is now online in NSMB: maternal yolk carries microRNAs from the intestine to embryos, shaping gene regulation and stress resilience in the next generation.
rdcu.be/fj8Er
#Epigenetics #microRNA #Inheritance @pasteur.fr @devstempasteur.bsky.social @erc.europa.eu
www.nature.com
Hiten Madhani
In this study, the authors use the Caenorhabditis elegans model organism to show that maternal microRNAs are delivered from the intestine to embryos by the yolk, where they regulate gene expression an...
If you want to know what 3′UTRs with long conserved sequence stretches do, check out our BioRxiv preprint doi.org/10.64898/202....
They form functional intermolecular 3′UTR-3′UTR interactions that enable co-folding of proteins to rapidly induce transcriptional programs.
The Cecere Laboratory
And now it's out! Happy that PNAS selected for the cover this SEM image snapped by @samjlord.bsky.social, one of the most evocative visualizations of Euplotes that I have ever encountered.
www.pnas.org/doi/10.1073/...
Stay tuned for what is shaping up to be some fascinating follow-up in the lab...
Kristian G. Andersen
Christine Mayr
Ben Larson
What could be more exciting than watching Euplotes scurry around under the microscope? How about adding some raptorial predation by supergiant cannibal cells?
www.biorxiv.org/content/10.1...
Video by Vittorio Boscaro.
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