New work out today introducing PCIPs, heterobifunctional chemical inducers of proximity that inhibit DNA repair by recruiting BET proteins to PARP2. Great work uncovering a new form of event-driven pharmacology by Bryce/Eric/Erin and the rest of the team. (1/3)
www.biorxiv.org/content/10.1...
Chemical inducers of proximity (CIPs) can elicit durable, and often neomorphic, biological effects through the formation of a ternary complex, even at low equilibrium occupancy of their targets. This ...
Excited to share our latest work developing molecular glue degraders of ZBTB11, now out in @natchembio.nature.com
www.nature.com/articles/s41...
📣 Calling all ubiquitin aficionados - one week to go before abstract deadline (July 18th)!! Join us on the coast in Lorne, Australia. www.lorneubiquitin.org
#ubiquitin
Download and distribute our (massive) database of funding opportunities and fellowships for POSTDOCs
Cuts across all fields of research. 293 fellowships with info about deadline, amount, field, eligibility, etc.
Good luck!
Download this database freely here: research.jhu.edu/rdt/funding-...
‼️ Call for Nominations🏅Chi-Huey Wong Chemical Biology Award
1️⃣ Official Nomination Form
2️⃣ Nomination Letter (maximum 1,000 words)
🙅 Self-nominations will not be considered
📅 Nominate before October 31, 2025
👉 Ms. Marene Chan
📧 [email protected]
🌐 chemistry.org.tw/award_chwong/
Depletion of a transcriptional factor ZBTB11 using molecular glue degraders can overcome oxidative-phosphorylation-mediated KRAS inhibitor resistance in pancreatic ductal adenocarcinoma with low acute...
🚨 New preprint!
Excited to share our latest work, led by @sauravk05.bsky.social (Nabet lab) and Jiewei Jiang (Ferguson lab), on targeting oncogenic TRK fusions. We report potent and selective degraders of TPM3-TRKA, a driver of adult and pediatric cancers. www.biorxiv.org/content/10.1...
📢We are delighted to announce that @fleurmferguson.bsky.social (@ucsandiego.bsky.social) has been awarded the 2025 RSC Medicinal Chemistry Emerging Investigator Lectureship! Please join us in congratulating her 🎉 #medchem #chemsky
Find out more about Fleur here🔽
blogs.rsc.org/md/2026/03/1...
📢Know someone worthy of the @rscbmcs.bsky.social Hall of Fame?
Nominations are open for the 2026 inductee recognising a prominent chemist for outstanding, sustained contributions to areas of interest to the BMCS #chemsky #chembio #medchem
Find out how to nominate🔽
www.rscbmcs.org/awards/hallo...
Incredibly honored to be named a 2025 Pew Scholar in the Biomedical Sciences! 🧬 Grateful to Pew Trusts for this recognition and support, and to my awesome lab team, mentors and colleagues at @ucsdhealthsci.bsky.social Excited for what's ahead!
www.pew.org/en/about/new...
Fleur Ferguson
Chromosomal translocations leading to the fusion of tropomyosin receptor kinases (TRK) with diverse partner proteins have been identified as oncogenic drivers in many adult and pediatric cancers. Whil...
We are looking to hire an Assistant/Associate Professor interested in creating an innovative (and exciting) program of research in chemical biology, medicinal chemistry, ML/AI, drug discovery - all in the context of cancer biology!
careers.dana-farber.org/job/11813/as...
IUPAC
Assistant/Associate Professor, Chemical Biology job
