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Excited to share our latest work developing molecular glue degraders of ZBTB11, now out in @natchembio.nature.com www.nature.com/articles/s41...
10mo
ZBTB11 depletion targets metabolic vulnerabilities in KRAS inhibitor-resistant PDAC - Nature Chemical Biology
Depletion of a transcriptional factor ZBTB11 using molecular glue degraders can overcome oxidative-phosphorylation-mediated KRAS inhibitor resistance in pancreatic ductal adenocarcinoma with low acute...
www.nature.com
Fleur Ferguson
