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Associate Professor at Oregon Health & Science University studying microbial interference in host ubiquitin signaling. Current ASM Northwest Branch President. Formerly @UWBiochemistry and @MRC_LMB.
Jonathan Pruneda









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Online Now: TRIM21 induces selective autophagy of viruses and bacteria Online now:
Dual-channel Cx46/50 gap junction assemblies in a shared lipid-nanodisc = lipid-mediated packing and a lipid site near the NT gating region that is absent from single channels. Plus a 1.8 Å open-state single-channel benchmark! #cryo-EM 🍩’s #NIH-funded-research www.biorxiv.org/content/10.6...
One week left to apply for two 3-year postdocs in the lab on molecular mechanisms of Burkholderia pathogenesis. Posts associated with Magdalen College. Our lab is based in the Dunn School of Pathology with amazing collaborators at Oxford and MORU magdalencareers.pinpointhq.com/postings/c90...
Only a couple of days left to register for the UK Cellular Microbiology Network Meeting - we will have a great line up of speakers and poster presenters investigating various pathogens in cell-based, tissue and in vivo models.
Thrilled to announce that the Department of Microbiology at the University of Washington, School of Medicine is hiring at the Assistant Professor level (tenure-track)! The Pacific Northwest is an awesome place to live and do science 🧪🦠. Join us! apply.interfolio.com/185622 Applications due 8/1.
Postdocs - if you want to work on killer yeasts - I am HIRING. uidaho.peopleadmin.com/postings/51451 CLOSING SOON!
MMI faculty member Isabella Rauch @rauchlab.bsky.social gave the @globalimmuno.bsky.social seminar today. You can find the recording on youtube at urldefense.com/v3/__https:/...
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10 days left to register for the 2026 EMBO ubiquitin conference! Join us in coastal Puglia, for a jam packed schedule on all things ubiquitin (and friends). Fantastic line up of speakers and an impressive amount of opportunities for ECRs and networking. meetings.embo.org/event/26-ubi...
Interested in microbiology, immunology, and host-pathogen interactions? Come work with us! Our department at OHSU is opening a search for a new tenure-track faculty position. See the job advertisement for details. Please share within your networks! www.nature.com/naturecareer...
Rhinesmith et al. describe an intracellular antimicrobial mechanism called “antibody-directed xenophagy” (ADX). In ADX, the E3 ubiquitin ligase TRIM21 prevents infection by intercepting antibody-coated viruses/bacteria in the cytosol and orchestrating their destruction via selective autophagy. The authors hypothesize that ADX may be co-opted for targeted protein degradation.
TRIM21 induces selective autophagy of viruses and bacteria
dlvr.it
Job Opening: Calleva Centre Postdoctoral Researchers- The deadly enigma of melioidosis: Decoding the pathogenesis of Burkholderia pseudomallei. at Magdalen College in Central Oxford.
magdalencareers.pinpointhq.com
Calleva Centre Postdoctoral Researchers- The deadly enigma of melioidosis: Decoding the pathogenesis of Burkholderia pseudomallei.
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Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
22d
1mo
Molecular Cell
Patrick S. Mitchell
Over the past 5 years, 50 structures of full-length HECT-type ligase constructs have been deposited in the PDB. What have we learned from these studies, and what key questions remain open? Check out our new review on this exciting and fast-moving field: www.jbc.org/article/S002...
Gunnar N. Schroeder
Paul Rowley
Teresa Thurston
www.nature.com
The Department of Molecular Microbiology and Immunology at OHSU invites applications for a tenure-track Assistant or Associate Professor position.
Faculty Position in Molecular Microbiology and Immunology - Portland, Oregon job with Oregon Health & Science University (OHSU) - Molecular Microbiology and Immunology | 12858852
OHSU-MMI
Reichow Lab
28d
Share your videos with friends, family, and the world
urldefense.com
Jonathan Pruneda
YouTube
Ubiquitin coordinates a complex network of cellular pathways through covalent modification of substrates. Specificity in substrate recognition and modification choice is largely conferred by ubiquitin...
www.jbc.org
HECT-type ubiquitin ligases: Emerging principles in the era of full-length structures
Rachel O'Dea
Lorenz Lab