Ph.D Stem Cells and Regenerative Medicine @TajbakhshLab.bsky.social @pasteur.fr
Liza Sarde
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My first-author PhD paper is out in @natcomms.nature.com 🙌 We developed unique in vivo/ex vivo live-imaging pipelines to uncover new muscle stem cell behaviors in #DuchenneMuscularDystrophy.
Big thanks to all co-authors & the @tajbakhshlab.bsky.social lab!
www.nature.com/articles/s41...
🔬This paper explores the role of the primary cilium in neuronal migration. Using live-imaging, this study demonstrates the mechanosensory function of GPR161 receptor and its role on the cAMP/PKA signaling pathway, which in turn regulates the organization of the microtubule cage around the nucleus.
Our work investigates the dynamics of muscle stem cells in DMD pathology. We demonstrate stem cell migration impairment (fibre dependent) and premature differentiation driven by unbalanced symmetric divisions (fibre independent, regulated by Pi3K/Akt and p38)🎥💪🐭
Unique opportunity to join the CytoMorpho Lab (in Paris ❤️) as a postdoc to work on the self-organization and polarization of reconstituted networks made of microtubules, motors and actin filaments in vitro. Experience required.
Please Repost 🙏 thanks !
A work that took years to implement several quantitative live imaging pipelines. Worth the wait!! Beautiful results that give new insights into normal and dystrophic myogenic cell behavior and their dialogue with the niche. Kudos Liza, Brendan and colleagues.
🎉Excited to see my master’s work contributed to this amazing paper! 🎥 🧠
Congrats to all co-authors 👏
Grateful for my time in Dr. Isabelle Caillé & Pr. Alain Trembleau’s lab #IBPS. Isabelle’s passion for science will keep inspiring me ✨
doi.org/10.1126/scia...
Excited to share that the preprint of my Ph.D. work is now available! 🎉 Huge thanks to my amazing co-authors for their support and collaboration: @gaellel.bsky.social, H. Varet, V. Laville, J. Fernandes, @tajbakhshlab.bsky.social, @brendan-evano.bsky.social.
@devstempasteur.bsky.social @pasteur.fr
Liza Sarde
Bravo Liza, Brendan and colleagues for the elegant work on multiple live imaging strategies to untangle mechanisms of muscular dystrophy! www.nature.com/articles/s41...
Now published in its final version! Congrats again to all the authors for the amazing work 👏
www.nature.com/articles/s41...
Liza Sarde
Tajbakhsh Lab
Liza Sarde
Using live-imaging in vivo and ex vivo, Sarde et al. show that dystrophic muscle stem cells have precocious differentiation through symmetric divisions and impaired migration, with differential impact...
