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Boosting the anti-cancer activity of human MAIT cells by getting them to use lactate & directing them using bi-specific engagers @ardeena-berisha.bsky.social @andyhogan82.bsky.social @jimmunol.bsky.social academic.oup.com/jimmunol/art... @maynoothuniversity.ie
1mo
Waggoner Lab
Delighted to share our latest paper out today - led by @ardeena-berisha.bsky.social - we show that we can boost the anti-cancer activity of human MAIT cells by getting them to use lactate & also directing them using bi-specific engagers as a proof of concept academic.oup.com/jimmunol/art...
1mo
Abstract. Mucosal-associated invariant T (MAIT) cells are unconventional T cells, which upon activation can display potent cytotoxic and cytokine-producing
academic.oup.com
Lactate conditioning reprograms mucosal-associated invariant T cell metabolism boosting effector function
Andy Hogan