Host metabolism balances microbial regulation of bile acid signalling | @nature.com
www.nature.com/articles/s41...
A family of host-derived bile acid–methylcysteamine conjugates functions as FXR antagonists, forming part of a microbiota-dependent metabolic network that regulates FXR-dependent physiology.
Very exciting findings that gut microbes drive sugar consumption via a FGF21, GLP-1 and FFAR4-mediated mechanism. A potential game changer for nutritional science and diabetes. 🥇