Today in @nature.com we introduce INSTALL, which bypasses mammalian DNA immune sensing to enable non-viral DNA integration with recombinases—a step toward safe, and mutation-agnostic genome editing. 🧬 🧵 (1/13)
www.nature.com/articles/s41...
@harvardmed.bsky.social @mgbresearch.bsky.social
We're seeking candidates, typically graduating seniors, for ~2 years of post-bac research experience before applying to graduate school, medical school, etc.
If you're interested to learn more about the next generation of medicines, please reach out and apply!
Back in June, at our MSMDS conference, we shared how researchers were advancing their work on gene editing for ACTA2 R179H.
Today, we can celebrate that this effort is now peer-reviewed & published in @nature.com! 🎉
t.co/6WjTMRnAOi
#MSMDS #ACTA2 @markelindsay.bsky.social @bkleinstiver.bsky.social
Congratulations to CGM and Pathology Faculty Dr. Benjamin Kleinstiver (@bkleinstiver.bsky.social), winner of the 2026 Martin Prize in Fundamental Research!
Here's a link to the job posting where you can apply in the MGB career portal: massgeneralbrigham.wd1.myworkdayjobs.com/MGBExternal/...
Learn more about our research here: www.kleinstiverlab.org
An inspirational panel this morning with none other than baby KJ himself - highlighting the stories of heroes @ahrensnicklas.bsky.social & @kiranmusunuru.bsky.social ( hosted by @jasonmast.bsky.social).
Crescendo: KJ's Dad on watching 🏈 with his son: "This is what we thought we would never get". ❤️👏
Interested in gaining research experience, and curious about genome editing tool development and their application to treat human diseases? 🧬 🧫
We are hiring!! Join us at Mass General Hospital in Boston! 📣
massgeneralbrigham.wd1.myworkdayjobs.com/MGBExternal/...
Congrats to @connorjtou.bsky.social on being named a 2025 #STATWunderkind. His enthusiasm in the lab is contagious and he thrives on doing really hard things.
Really well deserved recognition for an innovator and emerging leader in our field! 👏 🙌
@mgbresearch.bsky.social @harvardmed.bsky.social
Connor Tou
Ben Kleinstiver
Ben Kleinstiver
Ben Kleinstiver
Ben Kleinstiver
CGM at MGB
Ben Kleinstiver
ACTA2 Alliance
INSTALL overcomes fundamental challenges for DNA delivery and integration methods by synergizing immune-stealth nucleic acids with recombinases to enable kilobase-scale integration strategies without ...
