Although cohesin-sensitive, long-range enhancer activation is equivalent in nature to proximal activation. Cooperativity can arise from different levels of activation inputs operating on a non-linear response function. @eliasfriman.bsky.social @uoe-igc.bsky.social
www.biorxiv.org/content/10.6...
This will be a great way to celebrate the achievements of MRC Human Genetics Unit PhD students - both current and past. Please share far and wide!
Wendy Bickmore
Excited to highlight the new Special Issue of RNA showcasing advances in system-level RNA biology, from epitranscriptomics and RNA damage to deep learning–driven structure prediction and beyond #RNAbiology #Epitranscriptomics #RNAseq #ComputationalBiology #Genomics bit.ly/4tEQL9I
Institute of Genetics and Cancer
Very harmonious and inspiring collaboration with Niels Gehring, @volkerboehm.bsky.social and team at Uni Köln, and colleagues at @mdc-berlin.bsky.social . Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome: Molecular Cell www.cell.com/molecular-ce...
Calling all alumni of the MRC Human Genetics Unit
Join us on Wednesday 23rd Sept to mark the last ever intake of PhD students to the HGU, and to celebrate the achievements of our alumni, and current PhD cohort.
To secure a place, please registerat:
www.eventbrite.co.uk/e/mrc-hgu-ph...
UPF1 depletion inhibits nonsense-mediated mRNA decay (NMD) and stabilizes direct target
transcripts within hours. Boehm et al. use conditional protein degradation and advanced
transcriptomics to map t...
www.cell.com
A drug candidate for hard-to-treat cancers, developed by Profs Neil Carragher and Asier Unciti-Broceta at #IGC and licensed to Nuvectis Pharma, has moved to the next stage of clinical trials. Read more here: edin.ac/3UuvJeo
@edinnovations.bsky.social
Our paper on a centromere-enriched retroelement is out! link.springer.com/article/10.1... Congratulations to all the authors! Comments and reposts welcome and appreciated 🧬🔬
www.eventbrite.co.uk
We hope you can join us for a fun and inspiring in-person gathering.
A drug candidate for hard-to-treat cancers, developed in the Institute of Genetics and Cancer (IGC) and now licensed to Nuvectis Pharma, has moved to the next stage of clinical trials after successful...
Background Centromeres depend on chromatin containing the conserved histone H3 variant CENP-A for function and inheritance, while the role of centromeric DNA repeats remains unclear. Retroelements are...
