The next (and last) session of the ISPB Virtual Seminars is coming up on 16 December
Don’t miss the closing of this amazing series! ✨
Save the date!!
#Plasmid #MGE #ISPB
Conjugative plasmids help spread AMR genes. @andrewmatthews.bsky.social @sonjalehtinen.bsky.social & @tatianadimitriu.bsky.social show that #AMR loss in evolving populations involves streamlined #plasmids that gain a transmission advantage by deleting AMR genes @plosbiology.org 🧪 plos.io/48NM0BL
We found that TIR domains in animal immune proteins, including the human TLR4, are enzymes that cleave NAD+ to produce the signaling molecule cADPR
Read our new preprint by talented Bohdana Hurieva: “Conserved catalytic activity of immune TIR domains in animals”
www.biorxiv.org/content/10.6...
New benchmark by @tclavel.bsky.social & @treichelnicole.bsky.social reveals that while 0.5 Gb works for profiling, de novo MAG assembly requires >10 Gb. Crucially, they found that only 55-82% of high-quality MAGs accurately represented original strains.
Full Article: doi.org/10.1038/s415...
Please remember that the International Symposium on Plasmid Biology (ISPB 2026) will take place 7–11 September 2026 in Berlin, Germany!
A great opportunity to meet, reconnect, and engage with the global plasmid biology community. 🤝
plasmid-biology-2026.de
Our story on plasmid streamlining is now published in PLoS Biology! With @andrewmatthews.bsky.social and @sonjalehtinen.bsky.social
#MicroSky #Mevosky
journals.plos.org/plosbiology/...
We've come full circle! I began my postdoctoral career by identifying the peptidyl deformylase gene. Today, we show that half of bacterial species harbor multiple PDF genes (up to 7, for always a single Met-tRNA transformylase), and while the role of these PDFs ... academic.oup.com/mbe/article/...
Today Is the deadline for abstract submissions ‼️
🐓 Bacteria trade resistance genes in the chicken gut, but the host may influence this exchange.
Small RNAs from chicken tissue modulate plasmid transfer between E. coli. 🧬
#Plasmid #Conjugation #miRNA
doi.org/10.1038/s442...
New online: Structure and activation mechanism of a Lamassu phage and plasmid defense system