New benchmark by @tclavel.bsky.social & @treichelnicole.bsky.social reveals that while 0.5 Gb works for profiling, de novo MAG assembly requires >10 Gb. Crucially, they found that only 55-82% of high-quality MAGs accurately represented original strains.
Full Article: doi.org/10.1038/s415...
The next (and last) session of the ISPB Virtual Seminars is coming up on 16 December
Don’t miss the closing of this amazing series! ✨
Save the date!!
#Plasmid #MGE #ISPB
Today Is the deadline for abstract submissions ‼️
Please remember that the International Symposium on Plasmid Biology (ISPB 2026) will take place 7–11 September 2026 in Berlin, Germany!
A great opportunity to meet, reconnect, and engage with the global plasmid biology community. 🤝
plasmid-biology-2026.de
We found that TIR domains in animal immune proteins, including the human TLR4, are enzymes that cleave NAD+ to produce the signaling molecule cADPR
Read our new preprint by talented Bohdana Hurieva: “Conserved catalytic activity of immune TIR domains in animals”
www.biorxiv.org/content/10.6...
🐓 Bacteria trade resistance genes in the chicken gut, but the host may influence this exchange.
Small RNAs from chicken tissue modulate plasmid transfer between E. coli. 🧬
#Plasmid #Conjugation #miRNA
doi.org/10.1038/s442...
Conjugative plasmids help spread AMR genes. @andrewmatthews.bsky.social @sonjalehtinen.bsky.social & @tatianadimitriu.bsky.social show that #AMR loss in evolving populations involves streamlined #plasmids that gain a transmission advantage by deleting AMR genes @plosbiology.org 🧪 plos.io/48NM0BL
New online: Structure and activation mechanism of a Lamassu phage and plasmid defense system
Our story on plasmid streamlining is now published in PLoS Biology! With @andrewmatthews.bsky.social and @sonjalehtinen.bsky.social
#MicroSky #Mevosky
journals.plos.org/plosbiology/...
We've come full circle! I began my postdoctoral career by identifying the peptidyl deformylase gene. Today, we show that half of bacterial species harbor multiple PDF genes (up to 7, for always a single Met-tRNA transformylase), and while the role of these PDFs ... academic.oup.com/mbe/article/...
Abstract. Peptide deformylases (PDFs) are enzymes that are essential for bacterial viability and attractive targets for antibiotic development. Yet, despit
Please remember that the International Symposium on Plasmid Biology (ISPB 2026) will take place 7–11 September 2026 in Berlin, Germany!
A great opportunity to meet, reconnect, and engage with the global plasmid biology community. 🤝
plasmid-biology-2026.de
