Passionate about ubiquitin biology, its mechanistic underpinnings and therapeutic exploitation? We are looking for a PhD student or postdoc to join our team. Applications and informal inquiries welcome!
www.mpinat.mpg.de/19-26?c=3895...
Fantastic to be back at Oxford, where I completed my PhD. The Biochemistry Department @oxfordbiochemistry.bsky.social continues to be a true powerhouse of excellence and innovation. A sincere thank you to @robklose.bsky.social and @elliottlab.bsky.social for the invitation and the inspiring science!
Over the past 5 years, 50 structures of full-length HECT-type ligase constructs have been deposited in the PDB. What have we learned from these studies, and what key questions remain open? Check out our new review on this exciting and fast-moving field: www.jbc.org/article/S002...
Thanks so much, Richard de Heiden and Monique Mulder, for featuring exciting findings on drug-like small-molecule ubiquitination by my research group and that of Jonathan Ostrem. Check out thisTiBS spotlight: www.sciencedirect.com/science/arti...
Tropical disease Leishmaniasis affects the world’s poorest regions. Scientists led by Thornton Fokkens & Sonja Lorenz @sonjalorenzlab.bsky.social have shown that leishmania parasites require the protein TKUL to maintain infections of host cells. 👇 (1/3)
Congratulations, Dr. Banos! I am so happy that we will have the opportunity to continue working together in the coming years. Thanks so much to all supporters of Blanca's research and career!
Exciting! Yet another Spotlight article has come out today in @cp-trendsparasitol.bsky.social, featuring our work on kinase-ligase crosstalk in a Leishmania virulence factor. Thanks so much, @jnpruneda.bsky.social and Shun-Je Bhark! www.sciencedirect.com/science/arti...
Exciting opening for a lab technician in the Rink department @mpi-nat.bsky.social:
www.mpinat.mpg.de/5123253/36-25
The lab is looking for a technician to support and develop next-generation sequencing applications. Please forward the announcement:
Allosteric activation of a ubiquitin ligase by an internal kinase domain! Congratulations to our team member Thornton Fokkens for this fascinating discovery in a neglected disease area with strong therapeutic need. Many thanks to all our great collaborators!
www.sciencedirect.com/science/arti...
Sledding to the lab - what a great way to start the year!
Have a fantastic 2026, everybody!
Ubiquitin coordinates a complex network of cellular pathways through covalent modification
of substrates. Specificity in substrate recognition and modification choice is largely
conferred by ubiquitin...
www.jbc.org
The research group Ubiquitin Signaling Specificity (Dr. Sonja Lorenz) invites applications for the position as
PhD student or Postdoc (f/m/d)
– Understanding and manipulating ubiquitin ligase specifi...
Recent reports by Orth, Pohl, et al. and Li, Garcia-Rivera et al. show that ubiquitin can mark drug-like molecules in cells. This non-canonical ubiqui…
www.sciencedirect.com
Leishmaniasis, a neglected tropical disease caused by Leishmania parasites, poses an immense global health burden in desperate need of additional foun…
Die Abteilung Gewebedynamik und Regeneration (Prof. Dr. Jochen Rink) sucht eine
Technische Assistenz (w/m/d) - zur Unterstützung und Entwicklung von Next-Generation Sequencing Anwendungen -
www.mpinat.mpg.de
Stringent control of ubiquitylation is a central requirement of signaling specificity in eukaryotes. Here, we discover a domain module integrating pro…
Blanca Baños receives a Marie Skłodowska-Curie Fellowship🥂🎉! Congratulations! Our postdoctoral researcher @sonjalorenzlab.bsky.social aims to decipher the structural mechanisms by which ubiquitin ligases build ubiquitin chains and to develop new strategies to identify their substrates.
