Delighted with this new paper. Key findings I'm most interested in following up:
- Mechanical cues impact cell shape long after the cue ends,
- Surface ectoderm (SE) cells have cryptic lamellipodia which may enable collective crawling,
- SE becomes progressively jammed
www.cell.com/current-biol...
Pérez-Verdugo et al. show that hindbrain neuropore closure is driven by surface ectoderm
actomyosin purse-string tension and active migration. These forces create reproducible
patterns of cell elongat...