Chemical biologist passionate about post-translational modifications (PTMs) and a keen interest in drug development. Professor at OHSU leading a team dedicated to unraveling the mysteries of PARPs and ADP-ribosylation.
Mike Cohen
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I am excited to share the first paper from the Saldivar lab! A special thank you to all who contributed.
Precise control of transcription condensates across S phase balances linker histone expression with DNA replication, ensuring genome stability: Molecular Cell www.cell.com/molecular-ce...
Super excited that our SEE-CITE photoaffinity labeling method is now out in @natchem.nature.com rdcu.be/ffBSC. Here we introduce a custom silyl ether cleavable linker between a diazirine photocrosslinker handle and molecules of interest to streamline site-of-labeling analysis for PAL chemoproteomics
Registration has been reopened to fill the last few remaining spots! Last chance to join us in Leiden this June!
New work from my team, identifying drug targets in M. abscessus. Pre-print posted here:
www.biorxiv.org/content/10.6...
Is arginine the new cysteine?! Check out our lab's latest in collaboration with @ianseiple.bsky.social's team where we introduce ninhydrin as a selective covalent warhead and probe targeting reactive arginines.
www.biorxiv.org/content/10.6...
Did you miss the original abstract deadline? No worries, we’ve extended it to January 30th! Don’t miss your chance to be part of an exciting meeting highlighting the cutting edge of the field.
Registration deadline extended to January 31, 2026. Join us @nucleosomepolice.bsky.social @leunglab.bsky.social at CSHL for the PARP Meeting—connect with leaders and rising stars from academia and industry. Please kindly repost!
.https://meetings.cshl.edu/meetings.aspx?meet=parp
Looking forward to the biannual #CBP2025 conference @ohsunews.bsky.social starting this week! incredible line up of speakers, including keynotes @mbogyo.bsky.social, @christhechang.bsky.social, and Nancy Carrasco.
www.ohsu.edu/school-of-me...
Just two more days to submit abstracts for the "PARP Family and ADP-ribosylation CSHL meeting. We have an amazing lineup of speakers. The majority of speakers are selected from abstracts. Don't miss out! meetings.cshl.edu/meetings.asp...
The best two years you can spend before graduate school! Get the hands of a 4th-year grad student contributing to Open Science: bit.ly/47mU5xx Or join an interdisciplinary AI/biology team (don't worry, the AI still needs you to do the actual experiments): bit.ly/4taqzni Both at Janelia!
Marmolejo et al. uncover transcription condensate dynamics at histone locus bodies
across the cell cycle. These dynamics are governed by cell cycle (DDK and CDK1/2)
and checkpoint (ATR-CHK1) kinases t...
Primary Work Address: 19700 Helix Drive, Ashburn, VA, 20147 Current HHMI Employees, click here to apply via your Workday account. Summary: We are seeking a chemist to join the Tool Translation Team, "...
The pathogen Mycobacterium abscessus ( Mab ) can cause severe and difficult to treat chronic lung infections. Despite the rising incidence and clinical concern of Mab infections, treatment options are...
Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.
Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.
Covalent molecules have emerged as next-generation therapeutics and as powerful tools for perturbing fundamental biological processes. Chemical proteomic methods to screen for reactive proteinaceous a...
Explore #immunology, #virology, #microbiology and more at EMBO Workshop "Pathogen Immunity and Signalling" in Leiden, NL, 8–11 June 2026.
Abstract submission/Registration deadline: 1 February/15 March
https://meetings.embo.org/event/26-pathogen-immunity
#EMBOpathogenSignalling #EMBOevents 🧪
Just two more days to submit abstracts for the "PARP Family and ADP-ribosylation CSHL meeting. We have an amazing lineup of speakers. The majority of speakers are selected from abstracts. Don't miss out! meetings.cshl.edu/meetings.asp...
Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.
Viruses, bacteria, and other pathogens pose a serious threat to human health, requiring a coordinated response from the innate and adaptive immune systems. Our immune system relies on pathogen recept…
