New PI @IMB in Mainz, Germany. Combining in vitro and in vivo approaches to study maternal mRNA regulation in 🐟 embryos.
Laura Lorenzo Orts
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Wanted:
Outstanding plant scientist and fantastic colleague.
If your science combines fundamental discovery with future applications, we would love to hear from you @dompsfr.bsky.social @biologyunifreiburg.bsky.social @cibss.bsky.social @uni-freiburg.de
uni-freiburg.de/en/job/00005...
Congratulations to Damián Martinez, Bruno Saraiva, @taylashakespeare.bsky.social, @wmarkbates.bsky.social, Dylan Owen, @christlet.bsky.social and @henriqueslab.bsky.social
We hope VLab4Mic helps researchers design better experiments and ask better biological questions
💻 vlab4mic.henriqueslab.org
New preprint by my former colleagues in the Pauli lab 🫶 When I first joined the lab, I naively thought Bouncer’s interacting partner was a single protein. Years later, it turns out that at least 7 components on the sperm side may mediate fertilization - meet the SPARK complex! ✨
Surprised to discover that Thermo Fisher appears to show a fake western blot for the validation of one of their p53 antibodies. I've added a diagram to show the very similar bands. This does not appear to be one of the "published figures" but their own internal data.
Dearest shoalmates:
Please consider posting a comment to the NIH regarding the Strategic Plan that includes reducing funding for animal research. Responses from the research community are currently greatly underrepresented compared w/ advocacy groups opposing animal experimentation.
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Congrats to Jirka Peschek and team from @bzh-hd.bsky.social for this exciting story on the conserved function of eukaryotic tRNA ligases to mediate RNA break repair, on the ribosome and beyond! We were happy to help and be involved.
This work nicely quantifies a major issue in our universities: "In higher education, administrative costs have risen much faster than instruction and research costs (4). MIT Faculty grew by only 9.2% between 1985 and 2023, while administrative staff grew by 189%." www.pnas.org/doi/10.1073/...
A Virtual Laboratory for Microscopy — simulate fluorescence microscopy experiments before stepping into the microscope room.
Open Postdoc Position - Giant E3 ligases: mysterious mechanisms & non‑protein substrates. Interested? Join us to uncover how these molecular giants tag lipids, RNAs, sugars beyond proteins, on organelles and pathogens, to defend the cell. Details & Application here www.imp.ac.at/career/open-...
Team effort from @fxrico.bsky.social, Oded, Pierre, Andrea, @hmchen93.bsky.social, Larissa now out in @pnas.org The Kelch phosphatase BSU1 is a PP1-like serine/threonine phosphatase involved in cell cycle regulation, not a tyrosine phosphatase in brassinosteroid signaling 👍 doi.org/10.1073/pnas...
New insights into #fertilization from the @pauligroup.bsky.social & Ikawa labs! In a tour-de-force study, we discovered ✨ SPARK ✨, a conserved sperm fertilization complex that couples sperm-egg binding to membrane fusion.
Read on 🧵👇 and check out our preprint for more details!
tinyurl.com/34cm4xat
