🐭 Female mice develop male genitals when researchers modified both copies of non-coding Enh13, which controls Sox9 gene responsible for testes development in male mice. This suggests Enh13 acts as an enhancer and a silencer of Sox9, per Nature Communications study.
#SciSky #MedSky 🧪
Small changes in the non-coding part of the genome have a key role in sex determination.
