President of the Albert and Mary Lasker Foundation (@laskerfdn.bsky.social). https://laskerfoundation.org
#InfectiousDiseases I #HIVResearch I #PublicHealth
Claire Pomeroy
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🧪US cancer mortality has shifted from highest in big cities to highest in rural areas, reversing since the 1990s for men & early 2000s for women, per Journal of the NCI study. This likely reflects geographic redistribution of social determinants of health, authors wrote: https://ow.ly/j7jL50Z5C2m
🧪SSRI fluvoxamine (but not metformin) may be an effective treatment for reducing fatigue and improving quality of life in patients with #longCovid, per Annals of Internal Medicine study of 399 adults in Brazil: https://ow.ly/js8O50Z6gua
Malaria may leave lasting effects on the brain, study in JAMA shows. Children who survived severe malaria scored worse on cognitive tests many years after infection, w/ a 4-7 pt IQ deficit vs controls. "It’s in the whole world’s interest to prevent this," one expert said: https://ow.ly/HCO750Z8SIE❤️🩹🧪
Traumatic head injuries from contact sports may cause lasting inflammation & long-term blood-brain barrier damage, per Science Magazine study. 🧪
🧠 MRIs of 47 retired athletes showed clear markers of barrier disruption, including altered expression of complement receptors: https://ow.ly/hA0o50Z6mqc
🧪Cytokine gene therapy helped calm inflammation in infected lungs of mice, per study in Science Magazine. Viral-vector delivery of interleukin-2, IL-1 receptor antagonist, & IL-10 reduced tissue injury after respiratory infection, alleviating severe respiratory infections: https://ow.ly/aQAx50Z8SVV
🧪Physical adversity (e.g. poor water quality and pollution) is associated with structural brain aging, and social adversity (e.g. socioeconomic inequality and low gross domestic product) is more associated with functional aging, per metastudy in @naturemedicine.bsky.social: https://ow.ly/Zf1350Z6gaL
Honored to be a judge for the American Junior Investigator Association (AJIA) "America's Got Research" shark tank—congratulations to all the presenters on great science and to the winners 🥇 Aleksandar Obradovic,🥈 Leo Wang, and🥉 Marty Spang. 🧪
🧪Among ~64K scientists whose careers spanned ≥40 yrs, researchers found that the probability of producing a top 10% disruptive paper declines sharply with career age. The findings, in Science Magazine, suggest older scientists are less likely to overturn established ideas: https://ow.ly/3p7I50Z8R30
