Please come by the Sohal lab posters at #SfN2025 to join the discussion about all of our favorite things: cognitive flexibility, gamma oscillations, PFC social encoding, autism mouse models, dopamine, & more!
Strikingly, inhibiting these synapses specifically after trial outcomes, locks them in a depotentiated state & prevents learning, showing that plasticity guides learning in real-time. Furthermore, gamma-frequency stimulation of these synapses reverses these deficits, restoring plasticity & learning.
