Study reveals cryo-EM structures of human MCM2-7 in G1-phase, showing autoinhibited SHs forming latched spiral. Insight into DNA replication intricacies in human cells! PMID:42151158, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-73118-9 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
TRIM21 induces selective autophagy of viruses and bacteria
Ribosomes are covered by a coat of flexible protein fragments www.biorxiv.org/content/10.64898/2026.06.18.733196v1 #cryoEM
More biologists are coding their own analyses. Next: version control.
Following this 30-min tutorial, you can learn how to use ChatGPT and GitHub Desktop to build a simple data dashboard.
GitHub helps you track changes, collaborate, and share your work.
Tutorial: gexijin.github.io/vibe/Git_Bra...
Autophagy, a key cellular process for nutrient management & quality control, when defective, can lead to cancer. Efficient autophagy helps in treatment resistance, making it a crucial target in… PMID:42151413, Nat Rev Drug Discov 2026, @NatRevDrugDisc https://doi.org/10.1038/s41573-026-01449-9
Precision by design: Surface plasmon resonance and the integration of biophysics in fragment-based drug discovery pubmed.ncbi.nlm.nih.gov/42317548/ #cryoEM
Structure of the NAT10 acetyltransferase and mechanism of tRNA acetylation pubmed.ncbi.nlm.nih.gov/42321159/ #cryoEM
The dynamic inositol phosphate network during development in Drosophila melanogaster https://www.biorxiv.org/content/10.64898/2026.06.18.733221v1
“The Website” is here! It can be intimidating getting into analysis of #CryoET data, and software is evolving all the time👩💻🚀. @phaips.vd.st & @florentwaltz.bsky.social put our lab’s workflows into an online guide. We hope this helps lower the bar to joining #TeamTomo. Feedback much appreciated! 🧪🧶🧬🔬