🚨 We discovered a new mode of Hox gene regulation in annelids! 🪱 A distal enhancer acts as a "global control region", lifting Hox genes from Polycomb repression. This is reminiscent of Hox gene control in vertebrates, but the two modes likely evolved convergently.
www.biorxiv.org/content/10.6...
Gene regulatory networks: from correlative models to causal explanations www.nature.com/articles/s41...
A fossil nervous system meets modern neurobiology.
We found that a living comb jelly preserves neural architecture remarkably similar to those inferred from Cambrian fossils over 500 million years old 🤩.
www.biorxiv.org/content/10.6...
Capolavoro 🎨 alert 🚨! What is the role of gene body methylation in invertebrates? Despite extensive speculation linking it to plasticity and environmental responses, its mechanistic effects and heritability remain unclear. Our take out in @natecoevo.nature.com: www.nature.com/articles/s41... 1/
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Does anyone have experience with the Gilson PipetMax 268 or 278, or any liquid handling robot, for combinatorial barcoding sci-RNA-seq/SPLiT-seq style workflows? We are interested in buying one for library prep automation. Any feedback welcome!
#singlecell #labautomation
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