Proud of this collaboration - our third paper on cisPT! Loved this one the most: a beautiful mix of high-res, low-res, and computational approaches. Grateful for this long-standing, truly fruitful team effort. Congrats to everyone!
peterslab (BIOCEV,CZ)
🚨It's finally out!🥂 | A few years after solving the structure of human cis-PT, we now tackle its dynamics in
@NatureComms
, revealing that a conserved interfacial loop serves as an allosteric hub, communicating with the active site to regulate catalysis. rdcu.be/eShjl
Nature Communications - This study shows how the NgBR subunit controls the activity of human cis-prenyltransferase, a key enzyme for protein glycosylation. Combined experimental and computational...
