This was literally cool work. ❄️ We locked ourselves in the cold room to slow down the HDX and catch even the fastest dynamics. Bonus: It turns out you can manually capture a 2-second exchange reproducibly (next time we set up the quench flow!).
💃🕺Happy to share a team effort to uncover the molecular "dance" behind human cis-prenyltransferase regulation!🔬🧬 @peterslab1.bsky.social @AlbGiacomello
#Biochemistry #StructuralBiology
@TAUMedFaculty @of_sagol biorxiv.org/content/10.1...
peterslab (BIOCEV,CZ)
Human cis-prenyltransferase (hcis-PT) synthesizes long-chain isoprenoids essential for N-linked protein glycosylation. This heteromeric complex comprises the catalytic subunit DHDDS and the regulatory...
