This is a really good read for anyone interested in DNA replication dynamics and the history and tools developed to study this complex process. Well done!
Michael Trakselis
New review in NAR!
We connect the two halves of the DNA replication field — single-cell microscopy and genome-wide sequencing to show how each method’s strengths build one picture: from DNA fibers → replication foci → origin & timing maps.
🔗 doi.org/10.1093/nar/gkag550
@narjournal.bsky.social
Abstract. Genome replication is without doubt the most complex and critical activity of all living cells. Any error may not only affect the cell itself but