Interested in Structural Biology, deep learning, NextFlow, HPC, viruses, missense mutations archaea, bacteria, evolution & random quirks of nature. (Protein Cosmos feed 🧶🧬) Leads a research group & Structural biology Facility,UNSW Sydney. Opinions my own.
Kate Michie
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What do you think, should I go and try to reclaim some of my gold from abcam?
Our paper is out today! See this news article on it. Asgard archea have some cool proteins. If you are interested in protein evolution it’s a really exciting space. I’m lucky to be a structural biologist in the age of DL🧬🧶 @brendanburns999.bsky.social @iduggin.bsky.social @debnathghosal.bsky.social
🧶🧬🤩 Useful! Thanks George.
Hey everyone, new targets are needed now more than ever! 🧶🧬 Please consider if you have something ready to go.
This should give our archaeal structural protein predictions a long-needed boost. This ‘dark space’ has been a frustrating limit and I’m excited to see the impact. Great work Pedro! 🥳🧶🧬
It’s my favourite famous human’s birthday today! Happy 100th Birthday Sir David Attenborough. How many of us went into careers in science inspired by him? When the world seem bleak he always reminds me to look at the wonder of the natural world to see something worth fighting for
🧶🧬Tomorrow ASBC community talks:Dr Cameron Gilchrist is talking about “Multiple protein structure alignment with FoldMason”
Wed 20th May
Sydney, Brisbane, Canberra, Melbourne, Hobart (AEST) : 1 pm - 2 pm
Adelaide (ACST): 12.30 pm - 1.30 pm
Perth (AWST): 11 am - 12 pm
For details of joining:
Archaea and bacteria reveal the ancient origins of another ‘eukaryotic’ complex. Membrane trafficking is old… check this out for an integrative approach showing how bioinformatics and computational structural methods marry with x-ray crystallography and cryo EM to reveal biology in all its beauty.🧶🧬
Big update for nf-core Proteinfold for protein people… check out v2. Great team effort! nf-co.re/proteinfold/...
Protecting the role of science as a global public good in an era of geopolitical competition: The International Science Council @sciencecouncil.bsky.social calls for the protection of scientific freedom, collaboration & capacity in an era of geopolitical fragmentation council.science/statements/s...
Stromatolites—and their close relatives, microbial mats—could be mistaken for what seems like a bunch of old dark rocks. But instead, they are dense, layered communities of microbes. Long before compl...
In this statement, the International Science Council calls for the protection of scientific freedom, collaboration and capacity in an era of geopolitical fragmentation, recognizing science as a global...
COMMD proteins assemble into a heterodecameric ring in the Commander complex, which plays a role in endosomal membrane trafficking and signalling in eukaryotes. Here, Liu et al. identify COMMD-like pr...
I'm happy to share the first pre-print of out Lab! 🎉
Introducing ArchaeaHQ
www.biorxiv.org/content/10.6...
We curated 21,644 genomes across all 4 archaeal kingdoms to bridge the gap in public datasets for computational biology
What is inside ArchaeaHQ... (1/2)
Pedro Leão
Join the quarterly meeting of the Australian Structural Biology Computing community. More information
Call for Targets: CASP17 (2026)
Depositors: Help advance the frontiers of structural biology by submitting your targets
Whenever I presented Phold, I was frequently asked "can you do the same beyond phages?" We ( @oschwengers.bsky.social @linsalrob.bsky.social @binomicalabs.org et al) finally did it with Baktfold github.com/gbouras13/ba... www.biorxiv.org/content/10.6...
nf-core/proteinfold 2.0.0 is out ✨
Now with Boltz, RoseTTAFold-All-Atom, HelixFold3, AlphaFold3, RoseTTAFold2NA, parallel execution, interactive HTML reports, comparative benchmarking reports, and many improvements.
Big thanks to all contributors ❤️🚀
nf-co.re/proteinfold/...
[2.0.0] - 2026-03-27
Enhancements & fixes
[#177] - Fix typo in some instances of model preset alphafold2_ptm.
[PR #178] - Enable running multiple modes in parallel.
[#179] - Produce an interactive...
Pipeline release! nf-core/proteinfold v2.0.0 - Montseny Brook Newt!
Please see the changelog: https://github.com/nf-core/proteinfold/releases/tag/2.0.0
nf-core
[2.0.0] - 2026-03-27
Enhancements & fixes
[#177] - Fix typo in some instances of model preset alphafold2_ptm.
[PR #178] - Enable running multiple modes in parallel.
[#179] - Produce an interactive...
