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Join @BiolaMJavierre as she unveils the first-ever gene regulatory roadmap of human B cell differentiation – linking chromatin architecture, enhancer activity, and disease risk across nine B cell subtypes.
Ever wondered how the 3D shape of DNA influences nucleosome spacing along chromatin? Dr. Vijay Ramani from the Gladstone Institute, will reveal fresh, unpublished insights on this topic, featuring a new method – LASSI – that tracks single-molecule sequence interactions in 3D.
Last reminder: We’ll see you bright and early at 9:30 AM EST on the 25th to kick off #chromatin2025! Fantastic lineup of speakers with discussion to follow each talk. Don’t forget to register for this virtual meeting if you haven’t yet: bit.ly/chromatin-2025
• Thanks to @ArimaGenomics for sponsoring #chromatin2025. Don't miss @_AnthonySchmitt and Matija Snuderl’s talk: Detection and characterization of chromosomal rearrangements from FFPE tumors using Hi-C, showcasing rapid 3D genomics for cancer analysis. In case you haven’t registered
Speaker Spotlight: Step inside the 3D genome of cancer with Dr. Kathryn Yost (@KatieEYost) from Whitehead Institute! She reveals how enhancer rewiring and genome architecture shape 15 human cancer types – discover tumor archetypes and new pathways hiding in the Cancer Genome Atlas. Don’t miss out:
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What controls how our genes switch on and off across the 3D genome? Dr. Bing Ren from @nygenome will dive deep into transcriptional insulators and the mysteries behind CTCF/Cohesin loop extrusion. Don’t miss his talk, ‘Mechanisms and Modulators of Transcriptional Insulators’ !
The Skok Lab is recruiting an experienced computational scientist to lead single-molecule epigenomic and 3D genome analysis. We integrate long-read sequencing with Hi-C/Hi-ChIP, scmulti-omics, and machine-learning to explore chromatin topology, and gene regulation.
February 20th is the deadline - register now for this exciting meeting
New preprint from the Skoklab
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