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📣 New preprint from the Jakobsson lab! We describe a detailed protocol to inhibit the expression of transposable elements in human pluripotent stem cells, developed thanks to @asapresearch.parkinsonsroadmap.org funding. Special shoutout to @anitaada.bsky.social! www.biorxiv.org/content/10.1...
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This protocol describes the workflow for transcriptional silencing of transposable elements (TEs) in human induced pluripotent stem cells (hiPSCs). The protocol illustrates how to design gRNAs to targ...
www.biorxiv.org
A framework for efficient CRISPRi-mediated silencing of retrotransposons in human pluripotent stem cells
ASAP Team Jakobsson