Congrats @drsusanna.bsky.social @ditalialab.bsky.social for solving the puzzle of how evolving gradient turns into spatial threshold responses. A beauty and quantitative tour de force. Full of nostalgia reading it. Did propose a temporal model ~20 yrs ago in thesis w/o data. Was quite wrong, tho 😂
@drsusanna.bsky.social paper is now out in its final form. Relative to the original preprint, we now show additional mutant data and a better way to display heat maps of gene activation.
www.cell.com/current-biol...
Using quantitative live imaging, Brantley et al. reveal that cells decode dynamic
BMP signaling during dorsal patterning of the Drosophila embryo by integrating activity
over time. These results advan...
