Cell biologist @INSERM @Sorbonne_Univ_, clathrin, dynamin, neuromuscular diseases, electron microscopy, metal replicas #CLEM
🔬🇪🇺 🇬🇷 🇨🇵
Stephane Vassilopoulos
Great to see this new review on super-resolution approaches to study the cytoskeleton doi.org/10.1016/j.jare.2026.04.056
And very glad to see our correlative STORM/PREM images of endocytic “clearings” with @christlet.bsky.social highlighted doi.org/10.1126/science.ado2032
Glad to see this out in the open! Preprint from Anna Brachet and colleagues from @iins-bordeaux.bsky.social looking at the relative organization and roles of ßII-/ßIII-spectrin in the dendritic membrane-associated periodic skeleton (MPS), including cool MINFLUX data: doi.org/10.64898/202...
A review on Super-resolution Structured Illumination Microscopy (SIM) to study endocytosis: pubs.acs.org/doi/10.1021/...
Featuring our live-cell SIM of proximal axons showing frozen clathrin-coated pits within clearing of the spectrin mesh (doi.org/10.1126/scie...)
The architecture of carriers formed by AP3:ARF1 for lysosomal membrane protein transport: www.science.org/doi/10.1126/.... Work from @jggkaufman.bsky.social, in collaboration with @dgershlick.bsky.social and David Owen. @mpibiochem.bsky.social @thecimr.bsky.social
@mhakala.bsky.social shows that HRS forms bidimensional condensates onto endosomal membranes to flatten clathrin/ESCRT-0, an observation unexplained since the 2000s. Thx to Kukulski lab, @stefvass.bsky.social @colomlab.bsky.social @kaksonen.bsky.social @mishakudryashev.bsky.social
rdcu.be/fihKk
Here's a hint...
Want to hear about axons, endo-exocytosis, and fancy microscopy? My recent talk to the Helmholtz Information & Data Science School For Health is available on youtube:
Tune in next Thursday and listen to @wiesner-t.bsky.social awesome project on exocytosis along the axon shaft!
Stephane Vassilopoulos
New perspective on caveolae www.nature.com/articles/s41...
link.springer.com/article/10.1...
AP3 generates clathrin-free carriers on endosomes by organizing via ARF1 dimers into elongated membrane-deforming arrays.
This Perspective discusses the mechanisms underlying both the formation and scission of caveolae, with a focus on highlighting the role of specific lipids in regulating and coupling these processes.
The Golgi apparatus expands during differentiation and increased secretory demand, yet the transcriptional mechanisms governing its biogenesis remain poorly defined. To investigate this process, we de...
A reminder: next Thursday, our monthly webinar will be taking place as usual.
To join us, kindly register via us06web.zoom.us/webinar/regi...
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Canadian Neuroscience Seminars – Postdoctoral Series (CNS-PDS)
