We’re looking for a postdoc to join us @ukdri.ac.uk @uclqsion.bsky.social! Strong immunology background to study neuroimmune interactions along gut–brain axis in Parkinson’s, supported by @wellcometrust.bsky.social. Collegiality & team spirit are a must. Info:
lnkd.in/eZSyHjND. Please help share 🙏
Excited to share our new work demonstrating a role for astrocytic inflammasome signaling in modulating hippocampal plasticity. @cp-immunity.bsky.social
All credit to Kristine Zengeler, who was the brains🧠 and muscle💪 behind this project and is a wonderful collaborator. www.cell.com/immunity/ful...
Absolutely thrilled & grateful to be awarded this prestigious ERC grant. None of this would have been possible without the remarkable team in my lab, past & present! Excited for the next steps of this important project.
Very excited and honored to join the Warsaw glia symposium- can’t wait to learn more about and discuss together the beauty and the complexity of glia with the community!
Dear immune/glia lovers of brain, gut and beyond… We’re looking for a lab tech/manager to join our team! Pls see details for application here ucl.ac.uk/work-at-ucl/se… @ukdri.ac.uk @uclqsion.bsky.social - pls help circulate among networks who’d be of interest, thank you!
🙏🙏 to entire team esp co-lead Tim Bartels. So proud of @seppedeschepper.bsky.social brilliant first postdoc who now leads his own at VIB. 🙏🙏🙏to @chanzuckerberg.bsky.social for supporting the project from early pilot phase. Contact us if u want to explore next steps in PD gut/brain neuroimmunology!
Our lab's 1st paper, led by @fchrisbennett.bsky.social & @waisenberg.bsky.social. A decade thinking how to directly assess the impact of microglia replacement. Yrs of hard work. This kind of work is needed to expand brain disease care for kids & the vision for safer, more effective cell therapy.
So great that this paper is finally out! Happy that I was able to contribute to this important study. Congratulations @seppedeschepper.bsky.social, @soyonhonglab.bsky.social, Tim Bartels and all co-authors!
New research has revealed how Parkinson’s spreads from the gut to the brain, with the help of immune cells – offering a new potential therapeutic strategy – in a study in mice co-led by Dr @soyonhonglab.bsky.social & Dr Tim Bartels @ukdri.ac.uk @uclqsion.bsky.social @uclbrainscience.bsky.social
Our paper is finally out!
We position intestinal muscularis macrophages as early initiators of α-synuclein pathology and dopaminergic neurodegeneration in Parkinson’s models. They also drive local CD4⁺ T cell expansion, which subsequently migrates from gut to brain
www.nature.com/articles/s41...
Soyon Hong
Soyon Hong
John Lukens
Soyon Hong
Soyon Hong
Soyon Hong
This link will take you to a page that’s not on LinkedIn
The function of immune pathways in homeostatic neurobiology remains underexplored.
Zengeler et al. find that the inflammasome complex, typically associated with immune
responses, is involved in memory...
Muscularis macrophages, housekeepers of enteric nervous system integrity and intestinal homeostasis, modulate α-synuclein pathology and neurodegeneration in models of Parkinson’s disease, and understa...
www.nature.com
James Conway
New research reveals how Parkinson’s spreads from the gut to the brain, with the help of immune cells – offering a new potential therapeutic strategy – in a study in mice led by scientists at the UK D...
Could targeting the gut's immune system tackle the early stages of Parkinson's? 🧠
A new study from @soyonhonglab.bsky.social & Tim Bartels (UK DRI at UCL) has revealed how Parkinson’s spreads from the gut to the brain - with the help of immune cells.
Read more 👉 www.ukdri.ac.uk/news-and-eve...
The results of the ERC Consolidator Grant call have been announced! 📣
349 researchers have been selected for funding. Congratulations to all! #ERCCogG!
👉 buff.ly/uu62uFV
#FrontierResearch #EUfunded #HorizonEurope
@scienceinnovation.ec.europa.eu
New research, led by Dr Soyon Hong and Dr Tim Bartels at the UK DRI at UCL, has revealed how Parkinson’s spreads from the gut to the brain, with the hel
Online now: Direct microglia replacement reveals pathologic and therapeutic contributions of brain macrophages to a monogenic neurological disease
We're back with another exciting session — this time, spotlight on microglial cells!
And wait until you see our star-studded lineup of speakers!
Don't miss it — join us and stay at the forefront of the latest research!
@soyonhonglab.bsky.social
#WGC #GLIA
European Research Council (ERC)
UK Dementia Research Institute
Immunity
The Warsaw Glia Community
Hematopoietic stem cell transplant is the gold standard for treatment of globoid cell leukodystrophy, also called Krabbe disease. Aisenberg et al. define the molecular signature of disease-associated macrophages (globoid cells) and demonstrate that brain-specific high-efficiency macrophage replacement in the twitcher model of Krabbe disease improves neuropathology, macrophage dysfunction, and survival.
<p>Nature, Published online: 28 January 2026; <a href="https://www.nature.com/articles/s41586-025-09984-y">doi:10.1038/s41586-025-09984-y</a></p>Muscularis macrophages, housekeepers of enteric nervous system integrity and intestinal homeostasis, modulate α-synuclein pathology and neurodegeneration in models of Parkinson’s disease, and understanding the accompanying mechanisms could pave the way for early-stage biomarkers.
