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So great that this paper is finally out! Happy that I was able to contribute to this important study. Congratulations @seppedeschepper.bsky.social, @soyonhonglab.bsky.social, Tim Bartels and all co-authors!
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Mitchell Bijnen
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<p>Nature, Published online: 28 January 2026; <a href="https://www.nature.com/articles/s41586-025-09984-y">doi:10.1038/s41586-025-09984-y</a></p>Muscularis macrophages, housekeepers of enteric nervous system integrity and intestinal homeostasis, modulate α-synuclein pathology and neurodegeneration in models of Parkinson’s disease, and understanding the accompanying mechanisms could pave the way for early-stage biomarkers.
Intestinal macrophages modulate synucleinopathy along the gut–brain axis
www.nature.com
Nature [Unofficial]