Interested to see how advanced microscopy holds the power to transform our understanding of therapeutics🔬🧠…come see our latest work. #AAIC25
Hall G session 2-3.30 pm integrative neuropathology in ADRD at 2.20 pm sharp
@drneurochic.bsky.social
🚨New in Lancet Neurology: Autopsy study of aducanumab in #Alzheimer’s shows superficial cortical Aβ cleared, but deeper persists. ARIA showed inflammation+ microinfarcts in leptomeningeal/penetrating vessels. Some path is PET-invisible. @drneurochic.bsky.social
authors.elsevier.com/a/1lxn85FFzL...
By going beyond ‘Atypical’ / ‘AD’ @jeffandthebrain.bsky.social got me excited about interesting unexplored avenues. And! A whole lot of relevant papers I still need to read. Check the recording @istaart.bsky.social available in ~3 weeks if you missed it!
At #ADPD2025?? Go check today&tomorrow Sarah Basile at poster 174 on #amyloid-beta nitration and its role in fibrillation and #neuroinflammation in #Alzheimer. We would LOVE to hear your thoughts!
Baayla Boon
Studying the proteome of amyloid-beta plaques in Alzheimer's disease without the need to perform immunohistochemical staining? Sounds like science-fiction but now possible thanks to this great collaborative project!!
@baaylab.bsky.social @axlmsg.bsky.social #proteomics #alzheimers 1/3