Amazing work from the Kellogg lab!! I had this kind of project in my very first 2022 professorship proposal and but never actually did it, super glad to see it can work in reality!!!
Martin Pacesa
Programmable DNA integration with New-to-Nature tools using Computational Protein Design [new]
creates simplified RNA-guided transposons by reconfiguring CAST machinery to interface with Cas9 for precise, robust DNA integration.
