Associate Professor @ UW-Madison Biochemistry. www.limlab.org
Telomeres, Cryo-EM, Single-molecule Biophysics. Opinions are my own. 🇸🇬
Ci Ji (CJ) Lim
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If you have experience in biochemistry/cryo-EM,
are interested in DNA replication, and would like to do a postdoc in New York - our lab has positions available! Just DM or email me with your CV.
Now online @pnas.org: We developed a simple, scalable, and accessible platform for deep profiling of phosphoeraser specificity using human phosphoproteome-derived peptide libraries (PhosPropels!) 🧪👩🔬https://www.pnas.org/doi/10.1073/pnas.2523183123
Jon Chen @jonchenjk.bsky.social and Claris Chong's review of recent in situ cryo-ET chromatin studies and our opinion on an important future genomic direction is now published in Current Opinions in Structural Biology.
www.sciencedirect.com/science/arti...
How do human cells defend against viruses?
@sgfern.bsky.social discovers that human immune proteins named ISGs target ancient features of replication shared between animal and bacterial viruses – opening analysis of human immunity to the power of bacterial genetics
www.biorxiv.org/content/10.6...
The results here re 3D classification are quite impressive. Would be interesting to see how much the LPP improves classification of near-native samples with extreme compositional heterogeneity (e.g. derived from cellular fractions)
