Neuromodulatory systems | Networks | Multimodal neuroimaging
Postdoctoral researcher at University of Oxford
Previously @MGHMartinos @KCL
timlawn.github.io/
Tim Lawn
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Here's a bit of unusual work on error processing and error awareness from our lab, which we've been working on off and on for around eight years: www.biologicalpsychiatrycnni.org/article/S245...
Details in thread
Conscious error detection is accompanied by error-related changes in phasic autonomic
activity. This autonomic response is diminished in older age – accompanied by impairments
in the conscious detecti...
Excited to see this out in PNAS. A fabulous project by Adam Pines and the Williams lab: across psychedelics (LSD, Psilo, MDMA), species, and datasets, a very consistent story—reduced propagation of activity into the default mode network (DMN). Congrats Adam! 🧠🍄
www.pnas.org/doi/10.1073/...
It has been super fun to work on this, where we learned that:
1) Mouse PFC is needed for model-based override of habits.
2) Separate PFC populations encode a 'policy' and the current 'value'.
3) The policy and value codes alternate theta sweeps towards the goal.
...and much much more!
What matters most for childhood brain organization?
We analyzed 649 variables.
The answer: Socioeconomics (SES); with brain patterns pointing at sleep & stress as drivers.
Even brain-IQ associations were better explained by SES.
In Science today: www.science.org/doi/10.1126/...
Want your mice to learn your task faster? 🐭 According to this paper giving a huge reward (10x typical size) in a subset of trials strongly shortens training times:
www.science.org/doi/10.1126/...
If these research directions resonate with you and you're interested in joining our team, we now have 2 open PhD positions!
More information about the positions: nextcloud.tuebingen.mpg.de/index.php/s/...
More information about our research: www.kyb.tuebingen.mpg.de/906930/natur...
#NeuroJobs
Paying peer reviewers works.
Expanded Fast & Fair experiment @biologyopen.bsky.social:
• 5.5 vs 37.7 working days to decision with reviews
• ~3 vs ~9 reviewer invitations per manuscript
• no reduction in editor-assessed review quality
• similar acceptance rates
www.biorxiv.org/content/10.6...
Psychedelic drugs are poised to become mainstream treatments, yet we lack a circuit-level
account of how they reshape brain activity. Emerging evid...
I'll be presenting two posters at OHBM this week - come say hi!
[0510] Spatial collinearity constrains multivariate molecular
enriched network estimation
↳ Monday & Tuesday
[1985] Locus Coeruleus Connectivity Confers Cognitive
Resilience in Preclinical Alzheimer’s Disease
↳ Wednesday & Thursday
Standard animal learning studies minimize individual reward magnitudes to maximize the repetitions of reinforced behaviors. We investigated how reward magnitude influences initial learning across five...
How do brains plan actions towards goals?
To get at this question we studied mice navigating complex mazes as goals changed on every trial 🧵
Work with @thomasakam.bsky.social @behrenstimb.bsky.social @kristorpjensen.bsky.social now on BioRxiv: www.biorxiv.org/content/10.6...
Video
How can we acquire new knowledge and skills on a daily basis while remaining the same person?
I'm excited to share our new preprint led by @hyejinjadelee.bsky.social & Ally Dworetsky tackling this question, just in time for #OHBM2026:
doi.org/10.64898/202...
🧵👇
#neuroskyence #PsychSciSky
Brain regions exhibit dynamic yet highly coordinated activity patterns that form large-scale functional networks measurable through resting-state correlations. While their association with fluctuating...
