Cell biologist/Geneticist. Princess Maxima Center for Pediatric Oncology - Utrecht, the Netherlands
Investigating the molecular adaptations that drive meiosis, and how meiotic factors are hijacked by cancer cells.
Gerben Vader
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Only two days to go until the “Mitotic Spindle: From Living and Synthetic Systems to Theory” meeting in Dubrovnik! This is the 4th time Nenad Pavin and I are organizing it, and it keeps growing with each edition. Can’t wait to see everyone in Dubrovnik!
shorturl.at/35Vff
Join us at the @themaximacenter.bsky.social!
werkenbijprinsesmaximacentrum.nl/en/vacancy/j...
Registration is still open for this great meeting! Sign up for the 32nd ‘Dutch Cancer Biology Meeting’, focussed on the biology of cancer, which will be organized on March 5-6, 2026 in Lunteren, NL
Registration: lnkd.in/ehKXDtpP
More info: www.dutchcancerbiology.nl
@marcelvanvugt.bsky.social
All living organisms face the problem of parasites - but what happens when DNA has invaded the genome?
go.nature.com/3MDiJCq
Chromosomes stuck behind the spindle are ticking time bombs for aneuploidy. We uncovered a mechanical rescue mechanism where microtubule pivoting repositions these high-risk chromosomes! Out last week in @natcomms.nature.com, here's a thread 🧵
shorturl.at/OD89x
Mitosis has a timing system. If chromosomes attach properly, cells divide on schedule and keep proliferating. If attachment is slow or incomplete, the delay is recorded — and daughter cells stop dividing.
We explore this link in our new preprint.
🔗 www.biorxiv.org/content/10.6...
Mitosis lovers, get ready for Dubrovnik! 🔬🎉
I’m super excited to be organizing the 4th Mitotic Spindle Conference with Nenad Pavin, and we can’t wait to see you there!
Want your abstract to be selected for a talk? Submit by Feb 8!
www.phy.pmf.unizg.hr/~mitosis/
#SpindleCroatia2026
Excited to share our structural insights into how microtubules differentially guide phosphorylation of kinetochore-microtubule regulators, Ndc80 and MCAK, for chromosome segregation. Heroic efforts by Yiming Niu with a fun collaboration with Jennifer DeLuca lab!
www.science.org/doi/10.1126/...
Arianna Esposito Verza, @andrea-musacchio.bsky.social et al describe the long-sought-after mechanism of Bora dependency of PLK1 activation by Aurora A kinase during mitotic entry
Another #RefereedPreprint ℅ @reviewcommons.org
link.springer.com/article/10.1...
The newly established NeCEN Utrecht is looking for a #cryoEM scientist!
www.uu.nl/en/organisat...
Work with a new Krios 5 + pFIB and support cutting-edge life science research.
📍 Utrecht | 🗓 Apply by 30 April
Please share with your network!
Video
Video
Activation of PLK1, a master mitotic kinase, requires phosphorylation of its activation segment on Thr210, within a basic consensus sequence for Aurora kinases. Aurora B-dependent phosphorylation of T...
Join our team to contribute to the operation and innovation of state-of-the-art cryo-electron microscopes and empower groundbreaking research.
www.uu.nl
Gerben Vader
Gerben Vader
Iva Tolić
Iva Tolić
Iva Tolić
The position You will be responsible for establishing and leading your own research group. As a junior group leader you are expected to establish a unique and impactful line of research funded through...
Transposable elements can insert into genes, disrupting protein-coding potential. Researchers discover a mode of RNA processing, ‘SOS splicing’, that provides a quick fix.
Microtubules have been viewed as passive structural supports, but a study from @hirofunabiki.bsky.social in @science.org Advances redefines microtubules as active regulators, helping to prevent abnormalities in the number of chromosomes, a hallmark of cancer.
🔗: https://bit.ly/4v8miCC
Join us in Lunteren, the Netherlands on March 5 & 6, 2026 for the 32nd Dutch Cancer Biology meeting. We have two fantastic keynote speakers: @andrea-musacchio.bsky.social and @colindascheele.bsky.social and the rest of the program will be by early-career scientists. Info: www.dutchcancerbiology.nl
