Among the anti-recombinases, FIGNL1 rules them all. So much that inactivating it brings BRCA2-deficient cells to life. Who is responsible for RAD51 loading without BRCA2/FIGNL1, check out the paper to find out! Great collaboration with @raychaudhurilab.bsky.social
www.science.org/doi/10.1126/...
Our lab is featured in the latest Erasmus MC Annual Report. Thanks to my team, our collaborators and funding agencies for their continued support & making this possible! 🙏
Read here👇: digitaalpubliceren.com/erasmusmc/21...
www.linkedin.com/posts/oncode...
Today we are very pleased to share our latest article available now online @narjournal.bsky.social about the role of Slx4 scaffold and Fun30 (SMARCAD1 homolog) in DNA damage response regulation and replication fork protection against Top1-DNA crosslinks. academic.oup.com/nar/article/...
Thank you to @doksanilab.bsky.social, @nitikataneja.bsky.social, and everyone who joined us for such a great discussion today!
We’re excited to invite you to our next webinar on March 3rd with @centromellone.bsky.social and Michele Pagano.
Please note that the zoom link for tomorrow's webinar with @nitikataneja.bsky.social and @doksanilab.bsky.social has been updated:
uzh.zoom.us/j/6466274666...
Halloween borrel at the department 🎃 : our PhDs & Postdocs showed next-level creativity by revealing the hidden monstrous sides of their PIs! 👻😂
Absolutely hilarious & scary indeed😜… though I’m starting to wonder if that’s really how they see me 👀😅
Delighted & grateful to receive @erc.europa.eu support once again! This ERC-PoC will translate fundamental insights into therapy-induced chromatin reorganization toward proof-of-concept in ovarian cancer patient samples. Special thanks to @oncodeinstitute.bsky.social for continued support! 🙌
Delighted to be part of this work from the Lopes lab identifying nucleoplasmic Lamin A/C as a key regulator of replication fork plasticity, acting via de novo heterochromatin and ADP-ribosylation to control RECQ1-mediated fork restart. Now in Nature Comm. 🎉Special efforts: @joannapaulson.bsky.social
Another great science appointment is coming up with
@nitikataneja.bsky.social and @doksanilab.bsky.social!
Join us live on Tuesday, February 3rd at 5pm (Rome) / 11am (NYC).
Zoom link: uniroma1.zoom.us/j/95149984403
Register here to stay in the loop: docs.google.com/forms/d/e/1F...
Petr Cejka
🚨Great news: Oncode Investigators Nitika Taneja (Erasmus MC) and Sebastian Pomplun (LUMC) have been awarded European Research Council (ERC) Proof of Concept (PoC) funding.
As European Commissioner E...
Nature Communications - Replication fork plasticity upon genotoxic stress is modulated by nuclear architectural components by elusive mechanisms. Here the authors implicate Lamin A/C – best...
Thrilled to share our latest work - now available in full in Nature Communications - led in my lab by @vcherdy.bsky.social, with key collaborative contributions from @nitikataneja.bsky.social .
rdcu.be/eVrxX
Lopes_Lab
Nature Communications - Replication fork plasticity upon genotoxic stress is modulated by nuclear architectural components by elusive mechanisms. Here the authors implicate Lamin A/C – best...
