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Last week, several undergraduate students from our group completed their honors thesis defenses. Congratulations to Celeste, Justin, Melody, and Kayla on this milestone! We are so proud of your hard work and wish you all the best in your next chapter!
1mo
By merging this method with carbonyl migration and established C–H oxidation chemistry, we are now able to apply nitrogen scanning in saturated systems!
Check out our recent work on aliphatic C-to-N atom swap enabled by NAHA chemistry! This strategy enables access to diverse saturated N-heterocycles from cyclic ketones or cyclic alkanes. See: chemrxiv.org/engage/chemr...
Last week, Cole successfully defended his PhD! He will be starting his postdoc at Northwestern University. Congratulations, Dr. Wagner! Wishing you all the best in the future!
Dong Group at UChicago
Check out our recent work on @chemrxiv.org : using our NAHA reagent, now we are able to remove the carbonyl group from cyclic ketones--through both reductive and annulative pathways! chemrxiv.org/doi/full/10....
5mo
5mo
Check out our latest work on @jacs.acspublications.org : a ligand-controlled enantioconvergent homologation enables efficient access to chiral tertiary alkyl boronates. Congratulations to Miao, @ankizxu.bsky.social and Coco! pubs.acs.org/doi/10.1021/...
1mo
Last week, Sohee successfully defended her PhD—congratulations! From the total synthesis of harziane diterpenoids in Snyder group to exploring NAHA chemistry with us over the past two years, what an impressive scientific journey. Wishing her all the best in her next chapter!
Check out our recent work on unstrained C–C activation! We report a site-selective C-demethylation of phenols and anilines enabled by a removable mono-directing group. Congrats to Yibin, Liyan, Linda, and Congjun @congjunyu.bsky.social ! pubs.acs.org/doi/full/10....
Our recent work on aliphatic CO-to-N atom swap enabled by NAHA chemistry, now online in @science.org ! Congratulations to Zining, Zhehan and Rong! www.science.org/doi/10.1126/...
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1mo
2mo
1mo
Dong Group at UChicago
Dong Group at UChicago
Dong Group at UChicago
It's EDITING day in @science.org chemsky which is exciting because I'm an editor🙃 Anyway we have three different papers on skeletal editing!
Dong Group at UChicago
Scanning nitrogen in sp3-rich scaffolds enabled by carbonyl-to-nitrogen atom swap
Medicinal chemistry campaigns routinely require access to series of saturated nitrogen heterocycle (SNH)–based analogs that place nitrogen at different positions to probe structure-activity relationsh...
www.science.org
Dong Group at UChicago
Dong Group at UChicago
Dong Group at UChicago
1mo
Dong Group at UChicago
Jake Yeston