Soft/Bio physics and materials professor at UC Santa Barbara.
https://labs.materials.ucsb.edu/saleh/omar/
Omar Saleh
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This summer in beautiful Santa Barbara we will run a 3-day conference on “Biological Physics of Biomolecular Condensates: Bridging Theory and Experiment” June 16 to 18th. Register now: www.kitp.ucsb.edu/activities/b...
APSMarch attendees: eat to bed early so you can get to the 8am session on Friday: Bioinspired phase separation, wi the Lorenzo Di Michele and many other great speakers.
8am sharp in the Hilton 4th floor Palos Verdes room
summit.aps.org/events/MAR-W64
“As a public university, we are stewards of taxpayer resources, and a payment of this scale would completely devastate our country’s greatest public university system as well as inflict great harm on our students and all Californians.” —UC President James B. Milliken
Omar Saleh
Jerelle Joseph
Check out our paper on transcriptional control of an artificial condensate, including engineering a feedback loop that includes phase separation. Led by the amazing @samwilken.bsky.social
New from us in @pnas.org :
We considered the limits of condensate diversity, and engineered DNA droplets to form 9 distinct, homotypic, coexisting phases. Very hard to do this except with nucleic acids. Probably you can make more than 9. (1/3)
New paper from us in PRL:
Precision measurements of DNA condensate droplets as modulated by diffusive (Ostwald) or enzymatic processes. We verify LSW models of Ostwald ripening at the level of single droplets (blue images), and observe dynamic scaling of the size distribution….
University of California
… With enzymatic degradation, a curious behavior in which droplets disappear while their avg radius stays constant (red images).
Lovely work by post doc fellow Michio Tateno. Check out the paper at the link.
doi.org/10.1103/x2pf...
…we further show that appropriate thermal processing lead to metastable jammed-droplet layers, which are kinetically stabilized by cages formed from the diverse immiscible phases… so new types of structure and dynamics are possible with this system (2/3)
Work led by spectacular student Aria Chaderjian, with key insights from @samwilken.bsky.social
Paper available here:
www.pnas.org/doi/10.1073/...
(3/3)
8:00 am – 10:48 am, Friday March 21, Session MAR-W64, Anaheim Hilton, Palo Verdes (Level 4)
summit.aps.org
Omar Saleh
Omar Saleh
Omar Saleh
Omar Saleh
Omar Saleh
Omar Saleh
An experimental model system of DNA nanoparticles shows that the droplet size distribution can be controlled by the droplets' phase separation ability.
Breaking News: A Trump administration settlement proposal demands more than $1 billion from UCLA. It calls for the payout to contribute to a claims fund that would compensate victims of civil rights violations after a pro-Palestinian protest on campus.
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
We’re excited to share our new work in Soft Matter: doi.org/10.1039/D5SM...
We demonstrate how in vitro transcription can drive biomolecular phase separation — and how that phase separation in turn regulates transcription.
Sam Wilken
The Trump administration has ended about $500 million for the Los Angeles-based university. The president said he wanted nearly double that to restart the flow of funds.
Cells operate in part by compartmentalizing chemical reactions. For example, recent work has shown that chromatin, the material that contains the cell's genome, can auto-regulate its structure by util...