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We’re excited to share our new work in Soft Matter: doi.org/10.1039/D5SM... We demonstrate how in vitro transcription can drive biomolecular phase separation — and how that phase separation in turn regulates transcription.
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Cells operate in part by compartmentalizing chemical reactions. For example, recent work has shown that chromatin, the material that contains the cell's genome, can auto-regulate its structure by util...
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Condensation and activator/repressor control of a transcription-regulated biomolecular liquid
Sam Wilken